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Normal fibrinogen level in the blood

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Normal fibrinogen level in the blood
Last update: 04/05/2021

What is the normal level of fibrinogen in the blood?

Adults: 200-400 mg/dl
Children from 10 to 18 years old: 200 - 400 mg/dl
Children from 6 a 10 years old: 200 - 400 mg/dl
Children from 1 to 5 years old: 160 - 400 mg/dl
Babies up to 1 year old: 80 - 385 mg/dl
Newborns: 190 - 375 mg/dl

Why normal levels can differ across different labs?

Each laboratory must establish its own normal ranges for fibrinogen in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.

Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.

In pregnancy, normal range is usually higher. For this reason, it is necessary to follow the ranges marked by the laboratory in relation to the week of gestation.

What is the role of fibrinogen in the body?

Fibrinogen is a complex protein (polypeptide), which plays an important role in hemostasis, the process to prevent and stop bleeding.

For normal hemostasis to occur in response to injury or tissue damage, a sufficient concentration of fibrinogen must be present in plasma. Fibrinogen is converted into fibrin. Fibrin is necessary for the effective blood clot formation and is a key component of clot formation. The fibrin, along with platelets, forms the network for the common blood clot.

Fibrinogen is synthesized in the liver and it is naturally dissolved in plasma.

Fibrinogen is also known as clotting factor I. Fibrinogen is one of 13 coagulation factors responsible for normal blood clotting.

What is the fibrinogen blood test used for?

The fibrinogen blood test is part of a coagulation panel and it is performed when clotting disorders are suspected, for example, in case of intense nose, gums or menstrual bleeding. This test is also helpful when there is blood in the urine or the stool.

Although it is of primary importance as a coagulation protein, fibrinogen is also an acute-phase protein reactant. It is increased in diseases involving tissue damage or inflammation.

Besides, the fibrinogen blood test is used to study:

  • The presence of fibrinogen genetic disorders, resulting in a diagnosis of afibrinogenemia, hypofibrinogenemia or dysfibrinogenemia.
  • As an independent risk factor for cardiovascular disease (heart attacks or strokes). A higher value means a greater possibility to suffer one of them.

Low levels of fibrinogen may contribute to excessive bleeding, and conversely, levels that are above the normal range may contribute to the formation of small intravascular blood clots, causing thrombosis and cardiovascular problems such as a heart attack.

Where can I find more information about fibrinogen level in the blood?

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Which values are considered a normal fibrinogen level in the blood?

The following values are considered to be normal values:

IMPORTANT: These levels are expressed in mg/dL. They are an example of a healthy man/woman of about 45 years old, with a balanced diet, not known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Fibrinogen
Normality
200 mg/dl201 mg/dl202 mg/dl203 mg/dl204 mg/dl205 mg/dl206 mg/dl207 mg/dl
208 mg/dl209 mg/dl210 mg/dl211 mg/dl212 mg/dl213 mg/dl214 mg/dl215 mg/dl
216 mg/dl217 mg/dl218 mg/dl219 mg/dl220 mg/dl221 mg/dl222 mg/dl223 mg/dl
224 mg/dl225 mg/dl226 mg/dl227 mg/dl228 mg/dl229 mg/dl230 mg/dl231 mg/dl
232 mg/dl233 mg/dl234 mg/dl235 mg/dl236 mg/dl237 mg/dl238 mg/dl239 mg/dl
240 mg/dl241 mg/dl242 mg/dl243 mg/dl244 mg/dl245 mg/dl246 mg/dl247 mg/dl
248 mg/dl249 mg/dl250 mg/dl251 mg/dl252 mg/dl253 mg/dl254 mg/dl255 mg/dl
256 mg/dl257 mg/dl258 mg/dl259 mg/dl260 mg/dl261 mg/dl262 mg/dl263 mg/dl
264 mg/dl265 mg/dl266 mg/dl267 mg/dl268 mg/dl269 mg/dl270 mg/dl271 mg/dl
272 mg/dl273 mg/dl274 mg/dl275 mg/dl276 mg/dl277 mg/dl278 mg/dl279 mg/dl
280 mg/dl281 mg/dl282 mg/dl283 mg/dl284 mg/dl285 mg/dl286 mg/dl287 mg/dl
288 mg/dl289 mg/dl290 mg/dl291 mg/dl292 mg/dl293 mg/dl294 mg/dl295 mg/dl
296 mg/dl297 mg/dl298 mg/dl299 mg/dl300 mg/dl301 mg/dl302 mg/dl303 mg/dl
304 mg/dl305 mg/dl306 mg/dl307 mg/dl308 mg/dl309 mg/dl310 mg/dl311 mg/dl
312 mg/dl313 mg/dl314 mg/dl315 mg/dl316 mg/dl317 mg/dl318 mg/dl319 mg/dl
320 mg/dl321 mg/dl322 mg/dl323 mg/dl324 mg/dl325 mg/dl326 mg/dl327 mg/dl
328 mg/dl329 mg/dl330 mg/dl331 mg/dl332 mg/dl333 mg/dl334 mg/dl335 mg/dl
336 mg/dl337 mg/dl338 mg/dl339 mg/dl340 mg/dl341 mg/dl342 mg/dl343 mg/dl
344 mg/dl345 mg/dl346 mg/dl347 mg/dl348 mg/dl349 mg/dl350 mg/dl351 mg/dl
352 mg/dl353 mg/dl354 mg/dl355 mg/dl356 mg/dl357 mg/dl358 mg/dl359 mg/dl
360 mg/dl361 mg/dl362 mg/dl363 mg/dl364 mg/dl365 mg/dl366 mg/dl367 mg/dl
368 mg/dl369 mg/dl370 mg/dl371 mg/dl372 mg/dl373 mg/dl374 mg/dl375 mg/dl
376 mg/dl377 mg/dl378 mg/dl379 mg/dl380 mg/dl381 mg/dl382 mg/dl383 mg/dl
384 mg/dl385 mg/dl386 mg/dl387 mg/dl388 mg/dl389 mg/dl390 mg/dl391 mg/dl
392 mg/dl393 mg/dl394 mg/dl395 mg/dl396 mg/dl397 mg/dl398 mg/dl399 mg/dl
400 mg/dl       
Medically reviewed by our Medical staff on 04/05/2021

Bibliography

  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 299.
  • A Manual of Laboratory and Diagnostic Test. 9th edition. Frances Fischbach. Marshall B. Dunning III. 2014. Pag 171. ISBN-10: 1451190891.
  • Common Terminology Criteria for Adverse Events (CTCAE). Version 5.0.Published: November 27, 2017. U.S. Department of health and human Services. Disponible en: https://ctep.cancer.gov
  • Laboratory tests and diagnostic procedures with nursing diagnoses (8th ed), Jane Vincent Corbett, Angela Denise Banks, ISBN: 978-0-13-237332-6, Pag. 321.
  • Essentials of Medical Laboratory Practice. Constance L. Lieseke, Elizabeth A. Zeibig. 2012. ISBN: 978-0-8036-1899-2 Pag: 324.

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