High MPV level in the blood

If you need to know which are the MPV reference ranges or you require more information about the role of MPV in the blood, you can visit normal MPV level in the blood

The MPV (Mean Platelet Volume) measures the average size in volume of the platelets in the blood.

The MPV is usually higher when the production or destruction of platelets is also high.

It is possible to discern three different causes for a high MPV depending on the platelet count:

• Low platelet count: (thrombocytopenia)
  If the MPV is high and platelet count is low (thrombocytopenia) it may be due to a recovery after a severe bleeding or an ITP (immune thrombocytopenic purpura).
  When the MPV is high, the platelet size is similar to RBC (Red Blood Cells) and it is followed by thrombocytopenia (low platelet count) it may suggest a congenital thrombocytopenia.
  • With autosomal dominant inheritance: May-Hegglin, Epstein, Fechtner and Sebastian syndromes.
  • With autosomal recessive inheritance: Bernard Soulier syndrome.
• Normal platelet count
  If the MPV is high and the platelet count is in the normal range, it is usually due to hyperthyroidism or chronic myeloid leukemia.
• High platelet count (thrombocytosis)
  If the MPV is high and the platelet count is also high (thrombocytosis) it is usually due to an infection or an inflammation.

A high MPV increases the risk to suffer a heart disease.

The most common diseases why the MPV can be higher than normal are:

The MPV measurement is not related to the diet. Therefore, if you want to return MPV to normal range it is necessary to solve the underlying disease.

A high MPV value means that there is a higher risk to develop clots and heart problems. For this reason, if your doctor considers it appropriate, he can give prescribe you aspirin to reduce this risk.

The following values are considered to be above the normal range:

IMPORTANT: These levels are expressed in fl (femtoliter). They are an example of a healthy man/woman of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.