Normal MPV level in the blood

Each laboratory must establish its own normal ranges for MPV in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.

Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.

MPV means Mean Platelet Volume and measures the average size of platelets.

Platelets are blood cells that play a major role in blood clotting. The clot acts like a mesh to stop the bleeding. Platelets travel where there is an injury to form a mesh that plug the injury.

The MPV is the measurement of the average size of platelets found in blood and is typically measured in femtoliter (10^-15 liter).

The MPV is used as a help screen for or diagnose bleeding or clotting conditions. It must be used along with platelet count.

If MPV is higher than normal, the cause may depend on the platelet count:

• Normal or high platelet count: Chronic myeloid leukemia or hyperthyroidism.
• Low platelet count: ITP (Immune Thrombocytopenic Purpura) or preeclampsia.

If MPV is lower than normal, it may be due to:

• Normal platelet count: Kidney failure.
• Low platelet count: Aplastic anemia or chemotherapy.
• High platelet count: Infection, inflammation or cancer.

There are also many genetic diseases related to an altered MPV. The most common genetic disease that runs with a MPV high is Bernard Soulier syndrome and the most common one that runs with a MPV low is Wiskott-Aldrich syndrome.

The following values are considered to be normal values:

IMPORTANT: These levels are expressed in fl (femtoliter). They are an example of a healthy man/woman of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.