Blood test

Normal lipase level in the blood

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Normal lipase level in the blood
Last update: 22/12/2021

What is the normal level of lipase in the blood?

The normal range for lipase in the blood is age-dependent:

Adults over 60 years old: 26–267 U/L
Adults from 60 to 90 years old: 5–302 U/L
Adults from 20 to 60 years old: 31–186 U/L
Children: 20-136 U/L
Infant up to 1 year old: 9-105 U/L

In the International System of Units (SI), the lipase in the blood is measured in ukat/l. The normal lipase level in the blood in the SI is:

Adults over 60 years old: 0.44–4.54 ukat/L
Adults from 60 to 90 years old: 0.08–5.13 ukat/L
Adults from 20 to 60 years old: 0.53–3.16 ukat/L
Children: 0.34-2.31 ukat/L
Infant up to 1 year old: 0.15-1.78 ukat/L

Why normal levels can differ across different labs?

Each laboratory must establish its own normal ranges for the lipase in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.

Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.

Some circumstances may alter the normal ranges:

  • The substrates and the reactives used to measure the lipase level in the blood may be different in each laboratory, so the normal range may differ in different labs. The most widely used substrates are olive oil and triolein.
  • The lipase level fluctuates throughout the day.

What is the role of lipase in the body?

Lipase is an enzyme that changes fats and triglycerides into fatty acids and glycerol.

The lipase present in the blood is mainly produced by the pancreas, but can also be secreted in smaller quantities by the salivary glands as well as by the gastric and intestinal mucosa.

Lipase is filtered by the kidneys and totally reabsorbed by the renal tubules. That is why it is not normally detected in urine.

When there is a problem related to the pancreas the lipase in the blood increases.

What is the lipase blood test used for?

Lipase blood test is useful in the diagnosis and treatment of diseases of the pancreas, such as acute pancreatitis, or in case of obstruction of the biliary tract.

In acute pancreatitis, serum lipase begins to increase in 2–6 hours, peaks at 12–30 hours, and remains high, but slowly decreases for 2–4 days. Lipase rises and falls along with amylase in acute pancreatitis, but is a more specific marker for this condition.

Lipase may also be high in case of obstruction of the pancreatic duct, cholecystitis (inflammation of the gallbladder), kidney failure or diabetic ketoacidosis.

Where can I find more information about lipase in a blood test?

You can visit our pages about:

Which values are considered a normal lipase in a blood test?

The following values are considered to be normal values:

IMPORTANT: These levels are expressed in U/L. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Lipase
Normality
31 U/l32 U/l33 U/l34 U/l35 U/l36 U/l37 U/l38 U/l
39 U/l40 U/l41 U/l42 U/l43 U/l44 U/l45 U/l46 U/l
47 U/l48 U/l49 U/l50 U/l51 U/l52 U/l53 U/l54 U/l
55 U/l56 U/l57 U/l58 U/l59 U/l60 U/l61 U/l62 U/l
63 U/l64 U/l65 U/l66 U/l67 U/l68 U/l69 U/l70 U/l
71 U/l72 U/l73 U/l74 U/l75 U/l76 U/l77 U/l78 U/l
79 U/l80 U/l81 U/l82 U/l83 U/l84 U/l85 U/l86 U/l
87 U/l88 U/l89 U/l90 U/l91 U/l92 U/l93 U/l94 U/l
95 U/l96 U/l97 U/l98 U/l99 U/l100 U/l101 U/l102 U/l
103 U/l104 U/l105 U/l106 U/l107 U/l108 U/l109 U/l110 U/l
111 U/l112 U/l113 U/l114 U/l115 U/l116 U/l117 U/l118 U/l
119 U/l120 U/l121 U/l122 U/l123 U/l124 U/l125 U/l126 U/l
127 U/l128 U/l129 U/l130 U/l131 U/l132 U/l133 U/l134 U/l
135 U/l136 U/l137 U/l138 U/l139 U/l140 U/l141 U/l142 U/l
143 U/l144 U/l145 U/l146 U/l147 U/l148 U/l149 U/l150 U/l
151 U/l152 U/l153 U/l154 U/l155 U/l156 U/l157 U/l158 U/l
159 U/l160 U/l161 U/l162 U/l163 U/l164 U/l165 U/l166 U/l
167 U/l168 U/l169 U/l170 U/l171 U/l172 U/l173 U/l174 U/l
175 U/l176 U/l177 U/l178 U/l179 U/l180 U/l181 U/l182 U/l
183 U/l184 U/l185 U/l186 U/l    
Medically reviewed by our Medical staff on 22/12/2021

Bibliography

  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 520.
  • Tietz. Fundamentals of Clinical Chemistry. Carl A. Burtis, Edward R. Ashwood, David E. Bruns, Barbara G. Sawyer. WB Saunders Company, 2008. Pag 332. ISBN: 978-0-7216-3865-2.
  • A Manual of Laboratory and Diagnostic Test. 9th edition. Frances Fischbach. Marshall B. Dunning III. 2014. Pag 407. ISBN-10: 1451190891.
  • Common Terminology Criteria for Adverse Events (CTCAE). Version 5.0.Published: November 27, 2017. U.S. Department of health and human Services. Available on: https://ctep.cancer.gov

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