If you need to know which are the cholinesterase reference ranges or you require more information about the role of cholinesterase in the blood, you can visit normal cholinesterase level in the blood
A high level of cholinesterase in the blood is called hypercholinesterasemia and may be associated with various diseases and conditions, such as hyperlipidemia (high levels of lipids or fats in the blood), diabetes in patients with obesity, anxiety, mental disorders, or interactions with antiepileptic drugs. A significantly elevated cholinesterase level may also be related to nephrotic syndrome.
A high cholinesterase blood level means:
A high level of cholinesterase in the blood may be a consequence of diabetes with obesity, thyrotoxicosis, schizophrenia, hypertension, mood disorders or after a concussion.
If cholinesterase levels are very high, the most probable cause is due to nephrotic syndrome.
Warning: Normal range may differ from lab to lab depending of the type of cholinesterase measured, the sample, the technique or the substrate used to measure it. It is very important to check the normal range that appears in your report.
There are some health circumstances or drugs than can raise your cholinesterase level in the blood:
A cholinesterase level higher than normal may be a sign of the following diseases:
If your cholinesterase level in the blood is slightly elevated, you can try addressing potential causes such as obesity, diabetes, or high cholesterol. Additionally, if you are taking antiepileptic drugs, consult your doctor, as they may interfere with your cholinesterase levels.
There is a group of medications called acetylcholinesterase inhibitors (e.g., pyridostigmine, neostigmine) that can lower cholinesterase levels in the blood. These drugs are commonly used to treat conditions like myasthenia gravis or Alzheimer’s disease. However, an excessive dose may cause a cholinergic crisis.
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The following values are considered to be above the normal range:
IMPORTANT: These levels are expressed in U/ml. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.
Cholinesterase | |||||||
|---|---|---|---|---|---|---|---|
| Moderate cholinesterase increase | |||||||
| 18.1 U/ml | 18.2 U/ml | 18.3 U/ml | 18.4 U/ml | 18.5 U/ml | 18.6 U/ml | 18.7 U/ml | 18.8 U/ml |
| 18.9 U/ml | 19 U/ml | 19.1 U/ml | 19.2 U/ml | 19.3 U/ml | 19.4 U/ml | 19.5 U/ml | 19.6 U/ml |
| 19.7 U/ml | 19.8 U/ml | 19.9 U/ml | 20 U/ml | 20.1 U/ml | 20.2 U/ml | 20.3 U/ml | 20.4 U/ml |
| 20.5 U/ml | 20.6 U/ml | 20.7 U/ml | 20.8 U/ml | 20.9 U/ml | 21 U/ml | 21.1 U/ml | 21.2 U/ml |
| 21.3 U/ml | 21.4 U/ml | 21.5 U/ml | 21.6 U/ml | 21.7 U/ml | 21.8 U/ml | 21.9 U/ml | 22 U/ml |
| 22.1 U/ml | 22.2 U/ml | 22.3 U/ml | 22.4 U/ml | 22.5 U/ml | 22.6 U/ml | 22.7 U/ml | 22.8 U/ml |
| 22.9 U/ml | 23 U/ml | 23.1 U/ml | 23.2 U/ml | 23.3 U/ml | 23.4 U/ml | 23.5 U/ml | 23.6 U/ml |
| 23.7 U/ml | 23.8 U/ml | 23.9 U/ml | 24 U/ml | 24.1 U/ml | 24.2 U/ml | 24.3 U/ml | 24.4 U/ml |
| 24.5 U/ml | 24.6 U/ml | 24.7 U/ml | 24.8 U/ml | 24.9 U/ml | 25 U/ml | 25.1 U/ml | 25.2 U/ml |
| 25.3 U/ml | 25.4 U/ml | 25.5 U/ml | 25.6 U/ml | 25.7 U/ml | 25.8 U/ml | 25.9 U/ml | 26 U/ml |
| 26.1 U/ml | 26.2 U/ml | 26.3 U/ml | 26.4 U/ml | 26.5 U/ml | 26.6 U/ml | 26.7 U/ml | 26.8 U/ml |
| 26.9 U/ml | 27 U/ml | 27.1 U/ml | 27.2 U/ml | 27.3 U/ml | 27.4 U/ml | 27.5 U/ml | 27.6 U/ml |
| 27.7 U/ml | 27.8 U/ml | 27.9 U/ml | 28 U/ml | 28.1 U/ml | 28.2 U/ml | 28.3 U/ml | 28.4 U/ml |
| 28.5 U/ml | 28.6 U/ml | 28.7 U/ml | 28.8 U/ml | 28.9 U/ml | 29 U/ml | 29.1 U/ml | 29.2 U/ml |
| 29.3 U/ml | 29.4 U/ml | 29.5 U/ml | 29.6 U/ml | 29.7 U/ml | 29.8 U/ml | 29.9 U/ml | 30 U/ml |
| 30.1 U/ml | 30.2 U/ml | 30.3 U/ml | 30.4 U/ml | 30.5 U/ml | 30.6 U/ml | 30.7 U/ml | 30.8 U/ml |
| 30.9 U/ml | 31 U/ml | 31.1 U/ml | 31.2 U/ml | 31.3 U/ml | 31.4 U/ml | 31.5 U/ml | 31.6 U/ml |
| 31.7 U/ml | 31.8 U/ml | 31.9 U/ml | 32 U/ml | 32.1 U/ml | 32.2 U/ml | 32.3 U/ml | 32.4 U/ml |
| 32.5 U/ml | 32.6 U/ml | 32.7 U/ml | 32.8 U/ml | 32.9 U/ml | 33 U/ml | 33.1 U/ml | 33.2 U/ml |
| 33.3 U/ml | 33.4 U/ml | 33.5 U/ml | 33.6 U/ml | 33.7 U/ml | 33.8 U/ml | 33.9 U/ml | 34 U/ml |
| 34.1 U/ml | 34.2 U/ml | 34.3 U/ml | 34.4 U/ml | 34.5 U/ml | 34.6 U/ml | 34.7 U/ml | 34.8 U/ml |
| 34.9 U/ml | 35 U/ml | 35.1 U/ml | 35.2 U/ml | 35.3 U/ml | 35.4 U/ml | 35.5 U/ml | 35.6 U/ml |
| 35.7 U/ml | 35.8 U/ml | 35.9 U/ml | 36 U/ml | 36.1 U/ml | 36.2 U/ml | 36.3 U/ml | 36.4 U/ml |
| 36.5 U/ml | 36.6 U/ml | 36.7 U/ml | 36.8 U/ml | 36.9 U/ml | 37 U/ml | 37.1 U/ml | 37.2 U/ml |
| 37.3 U/ml | 37.4 U/ml | 37.5 U/ml | 37.6 U/ml | 37.7 U/ml | 37.8 U/ml | 37.9 U/ml | 38 U/ml |
| 38.1 U/ml | 38.2 U/ml | 38.3 U/ml | 38.4 U/ml | 38.5 U/ml | 38.6 U/ml | 38.7 U/ml | 38.8 U/ml |
| 38.9 U/ml | 39 U/ml | 39.1 U/ml | 39.2 U/ml | 39.3 U/ml | 39.4 U/ml | 39.5 U/ml | 39.6 U/ml |
| 39.7 U/ml | 39.8 U/ml | 39.9 U/ml | 40 U/ml | ||||