Adults 8-18 U/ml
In the International System of Units (SI), cholinesterase in the blood is measured in µkat/L. The normal cholinesterase level in the blood in the SI is:
Adults 133-300 µkat/L
Each laboratory must establish its own normal ranges for cholinesterase in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels, according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.
Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.
The normal ranges of cholinesterase in the blood may be very different from lab to lab depending of the type of cholinesterase measured (acetylcholinesterase, pseudocholinesterase or the sum of both), the sample (blood, plasma, serum, RBC), the technique or the substrate used to measure it. For that reason, it is very important to check the normal range that appears in your report.
Cholinesterase normal range in women is a bit lower than in men (10% or 15%). In newborns, normal ranges are usually half of the adult ones. The normal range of kids gradually increases to reach adult levels at 6 years old approximately.
In pregnancy, cholinesterase values are reduced a 20 or 30% in the first trimester, remaining decreased throughout the pregnancy and returning to normal range a few weeks after childbirth.
Cholinesterase is a family of enzymes made in the liver with an important role in the nervous system.
There are two types of cholinesterase:
Acetylicholinesterase is responsible for the prompt hydrolysis of acetylcholine released at the nerve endings to mediate transmission of the neural impulse across the synapse. The biological role of pseudocholinesterase is still unknown.
A cholinesterase blood test has three main purposes:
A high level of cholinesterase in the blood may be related to multiple diseases such as diabetes, hyperlipidemia, a high cholesterol level, hypertension, etc. If values are very high, it may be a sign of nephrotic syndrome.
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The following values are considered to be normal values:
IMPORTANT: These levels are expressed in U/ml. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.
|8 U/ml||8.1 U/ml||8.2 U/ml||8.3 U/ml||8.4 U/ml||8.5 U/ml||8.6 U/ml||8.7 U/ml|
|8.8 U/ml||8.9 U/ml||9 U/ml||9.1 U/ml||9.2 U/ml||9.3 U/ml||9.4 U/ml||9.5 U/ml|
|9.6 U/ml||9.7 U/ml||9.8 U/ml||9.9 U/ml||10 U/ml||10.1 U/ml||10.2 U/ml||10.3 U/ml|
|10.4 U/ml||10.5 U/ml||10.6 U/ml||10.7 U/ml||10.8 U/ml||10.9 U/ml||11 U/ml||11.1 U/ml|
|11.2 U/ml||11.3 U/ml||11.4 U/ml||11.5 U/ml||11.6 U/ml||11.7 U/ml||11.8 U/ml||11.9 U/ml|
|12 U/ml||12.1 U/ml||12.2 U/ml||12.3 U/ml||12.4 U/ml||12.5 U/ml||12.6 U/ml||12.7 U/ml|
|12.8 U/ml||12.9 U/ml||13 U/ml||13.1 U/ml||13.2 U/ml||13.3 U/ml||13.4 U/ml||13.5 U/ml|
|13.6 U/ml||13.7 U/ml||13.8 U/ml||13.9 U/ml||14 U/ml||14.1 U/ml||14.2 U/ml||14.3 U/ml|
|14.4 U/ml||14.5 U/ml||14.6 U/ml||14.7 U/ml||14.8 U/ml||14.9 U/ml||15 U/ml||15.1 U/ml|
|15.2 U/ml||15.3 U/ml||15.4 U/ml||15.5 U/ml||15.6 U/ml||15.7 U/ml||15.8 U/ml||15.9 U/ml|
|16 U/ml||16.1 U/ml||16.2 U/ml||16.3 U/ml||16.4 U/ml||16.5 U/ml||16.6 U/ml||16.7 U/ml|
|16.8 U/ml||16.9 U/ml||17 U/ml||17.1 U/ml||17.2 U/ml||17.3 U/ml||17.4 U/ml||17.5 U/ml|
|17.6 U/ml||17.7 U/ml||17.8 U/ml||17.9 U/ml||18 U/ml|