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Low amylase level in the blood

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Low amylase level in the blood

What does a low amylase level in the blood mean?

  • Hypoamylasemia

What is the normal level of amylase in the blood?

If you need to know which are the amylase reference ranges or you require more information about the role of amylase in the blood you can visit: Normal amylase level in the blood

What does a low amylase level in the blood mean?

A low level of amylase in the blood is not common and it is usually related to cardiometabolic disorders such as diabetes, fat intolerance or obesity.

In some cases, a low amylase level in the blood is due to a great intake of carbohydrates. Amylase is an enzyme present in the pancreas and the salivary glands. The amylase breaks down carbohydrates into smaller sugar molecules. If the intake of carbohydrates is excessive too much amylase is demanded and, consequently, the level of amylase in the blood may be low.

A low amylase level in the blood can be seen in severe pancreatitis or cystic fibrosis but is very rare in a routine assay.

  • Mild hypoamilasemia (0 - 28 U/dl in adults):

    The amylase level is a bit low and may be related to metabolic disorders. It may be due to a fat intolerance, suffering from diabetes or an excessive intake of carbohydrates.

    It is not usually a matter of concern but you can talk to your doctor and he will explain you if he considers it important along with the other blood tests performed.

Which factors can reduce the amylase level in the blood?

To suffer a particular health situation can reduce your amylase level in the blood:

  • Obesity
  • Drugs
    • Antibiotics
      • Gentamicin
    • Anticoagulants
      • Oxalates
    • Citrates

Which diseases can reduce your amylase level in the blood?

The following diseases can explain an amylase level in the blood lower than normal:

  • Type 1 diabetes
  • Type 2 diabetes
  • Diabetes mellitus
  • Metabolic syndrome
  • Fatty liver
  • Cystic fibrosis

What can I do to increase the amylase level in the blood?

If you want to increase the amylase level in the blood you can follow the next tips:

  • You should watch your weight and lose weight if you are obese.
  • Reduce the intake of carbohydrates in case your consumption was high.

Where can I find more information about amylase in the blood?

You can visit our pages about:

Which values are considered a low amylase level in the blood?

The following values are considered to be below the normal range:

IMPORTANT: These levels are expressed in U/L. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Amylase
Mild hypoamylasemia
27 U/l26 U/l25 U/l24 U/l23 U/l22 U/l21 U/l20 U/l
19 U/l18 U/l17 U/l16 U/l15 U/l14 U/l13 U/l12 U/l
11 U/l10 U/l9 U/l8 U/l7 U/l6 U/l5 U/l4 U/l
3 U/l2 U/l1 U/l0 U/l    
foto de Dr. Javier Muga Bustamante
Written by

Dr. Javier Muga Bustamante

Last update: 27/03/2020

Bibliography

  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 519.
  • Junge W, Wortmann W, Wilke B, Waldenstrom J, Weittenhiller A, Finke J, Klein G, Development and evaluation of assays for the determination of total and pancreatic amylase at 37°C according to the principle recommended by the IFCC. Clin Biochem 2001;34:607-615.
  • Lorentz K. Alpha-Amylase. In: Thomas L, hrsg. Labor und Diagnose. Indikation und Bewertung von Laborbefunden für die Medizinische Diagnostik. Frankfurt/Main: TH-Books Verlagsgesellschaft, 2005:51-56.
  • Tietz NW, ed. Clinical guide to laboratory tests, 3rd ed. Philadelphia: WB Saunders Company,1995:47pp.
  • Moss DW, Henderson RA. Clinical Enzymology. In: Burtis CA, Ashwood ER, eds. Tietz textbook of clinical chemistry. Philadelphia:WB Saunders Company, 1999; 689-692.
  • Junge W, Wortmann W, Wilke B, Waldenstrom J, Weittenhiller A, Finke J, Klein G, Development and evaluation of assays for the determination of total and pancreatic amylase at 37°C according to the principle recommended by the IFCC. Clin Biochem 2001;34:607-615.
  • Common Terminology Criteria for Adverse Events (CTCAE). Version 5.0.Published: November 27, 2017. U.S. Department of health and human Services. Disponible en: https://ctep.cancer.gov

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