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Normal vitamin B12 level in the blood

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Normal vitamin B12 level in the blood
Last update: 03/05/2022

What is the normal level of vitamin B12 in the blood?

The normal range for vitamin B12 in the blood is age-dependent:

Adults: 200 - 835 pg/ml
Children from 13 to 18 years old: 181 - 865 pg/ml
Children from 10 to 12 years old: 182 - 1088 pg/ml
Children from 7 to 9 years old: 246 - 1174 pg/ml
Children from 4 to 6 years old: 245 - 1406 pg/ml
Children from 2 a 3 years old: 264 - 1215 pg/ml
Children from 0 a 1 year old: 227 - 1514 pg/ml

In the International System of Units (SI), vitamin B12 in the blood is measured in pmol/L. The normal vitamin B12 level in the blood in the SI are:

Adults: 146 - 616 pmol/l
Children from 13 to 18 years old: 134 - 638 pmol/l
Children from 10 to 12 years old: 135 - 803 pmol/l
Children from de 7 to 9 years old: 182 - 866 pmol/l
Children from de 4 to 6 years old: 181 - 1038 pmol/l
Children from de 2 to 3 years old: 195 - 897 pmol/l
Children from de 0 to 1 year old: 168 - 1117 pmol/l

Why normal levels can differ across different labs?

Each laboratory must establish its own normal ranges for vitamin B12 in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels, according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.

Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.

What is the role of vitamin B12 in the body?

Vitamin B12, also known as cobalamin, is a vitamin synthesized by microorganisms that is naturally present in foods of animal origin. Meat is our primary source of vitamin B12.

For vitamin B12 intestinal absorption, it is necessary a protein called Castle’s intrinsic factor, secreted by the parietal cells of the stomach.

Vitamin B12 is crucial for normal red blood cell (RBC) formation. If there is a deficiency of vitamin B12, there will be not enough red blood cells in the blood and anemia will develop (lack of adequate transport of oxygen to the body's tissues).

Vitamin B12 also plays an essential role in the nervous system and it is necessary to prevent nerve damage.

In pregnancy, the developing fetus requires extra quantities of B12, so pregnant women are advised to consume vitamin B12 supplements.

What is the vitamin B12 blood test used for?

Vitamin B12 blood test is useful in case of macrocytic anemia, a type of anemia where there is a low level of hemoglobin in the blood with large red blood cells (RBCs).

Vitamin B12 blood test may give more information about this type of anemia. Macrocytic anemia is characterized by:

  • Anemia (low level of hemoglobin in the blood).
  • Macrocytosis or high MCV (Red Blood Cells larger than usual).

This test is commonly assessed with folate test (vitamin B9) to discern the underlying cause of macrocytic anemia.

It is also used for the follow-up of people diagnosed with pernicious anemia.

Where can I find more information about vitamin B12 in a blood test?

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Which values are considered a normal vitamin B12 in a blood test?

The following values are considered to be normal values:

IMPORTANT: These levels are expressed in pg/ml. They are an example of a healthy adult of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Vitamin B12
Normality
200 pg/ml201 pg/ml202 pg/ml203 pg/ml204 pg/ml205 pg/ml206 pg/ml207 pg/ml
208 pg/ml209 pg/ml210 pg/ml211 pg/ml212 pg/ml213 pg/ml214 pg/ml215 pg/ml
216 pg/ml217 pg/ml218 pg/ml219 pg/ml220 pg/ml221 pg/ml222 pg/ml223 pg/ml
224 pg/ml225 pg/ml226 pg/ml227 pg/ml228 pg/ml229 pg/ml230 pg/ml231 pg/ml
232 pg/ml233 pg/ml234 pg/ml235 pg/ml236 pg/ml237 pg/ml238 pg/ml239 pg/ml
240 pg/ml241 pg/ml242 pg/ml243 pg/ml244 pg/ml245 pg/ml246 pg/ml247 pg/ml
248 pg/ml249 pg/ml250 pg/ml251 pg/ml252 pg/ml253 pg/ml254 pg/ml255 pg/ml
256 pg/ml257 pg/ml258 pg/ml259 pg/ml260 pg/ml261 pg/ml262 pg/ml263 pg/ml
264 pg/ml265 pg/ml266 pg/ml267 pg/ml268 pg/ml269 pg/ml270 pg/ml271 pg/ml
272 pg/ml273 pg/ml274 pg/ml275 pg/ml276 pg/ml277 pg/ml278 pg/ml279 pg/ml
280 pg/ml281 pg/ml282 pg/ml283 pg/ml284 pg/ml285 pg/ml286 pg/ml287 pg/ml
288 pg/ml289 pg/ml290 pg/ml291 pg/ml292 pg/ml293 pg/ml294 pg/ml295 pg/ml
296 pg/ml297 pg/ml298 pg/ml299 pg/ml300 pg/ml301 pg/ml302 pg/ml303 pg/ml
304 pg/ml305 pg/ml306 pg/ml307 pg/ml308 pg/ml309 pg/ml310 pg/ml311 pg/ml
312 pg/ml313 pg/ml314 pg/ml315 pg/ml316 pg/ml317 pg/ml318 pg/ml319 pg/ml
320 pg/ml321 pg/ml322 pg/ml323 pg/ml324 pg/ml325 pg/ml326 pg/ml327 pg/ml
328 pg/ml329 pg/ml330 pg/ml331 pg/ml332 pg/ml333 pg/ml334 pg/ml335 pg/ml
336 pg/ml337 pg/ml338 pg/ml339 pg/ml340 pg/ml341 pg/ml342 pg/ml343 pg/ml
344 pg/ml345 pg/ml346 pg/ml347 pg/ml348 pg/ml349 pg/ml350 pg/ml351 pg/ml
352 pg/ml353 pg/ml354 pg/ml355 pg/ml356 pg/ml357 pg/ml358 pg/ml359 pg/ml
360 pg/ml361 pg/ml362 pg/ml363 pg/ml364 pg/ml365 pg/ml366 pg/ml367 pg/ml
368 pg/ml369 pg/ml370 pg/ml371 pg/ml372 pg/ml373 pg/ml374 pg/ml375 pg/ml
376 pg/ml377 pg/ml378 pg/ml379 pg/ml380 pg/ml381 pg/ml382 pg/ml383 pg/ml
384 pg/ml385 pg/ml386 pg/ml387 pg/ml388 pg/ml389 pg/ml390 pg/ml391 pg/ml
392 pg/ml393 pg/ml394 pg/ml395 pg/ml396 pg/ml397 pg/ml398 pg/ml399 pg/ml
400 pg/ml401 pg/ml402 pg/ml403 pg/ml404 pg/ml405 pg/ml406 pg/ml407 pg/ml
408 pg/ml409 pg/ml410 pg/ml411 pg/ml412 pg/ml413 pg/ml414 pg/ml415 pg/ml
416 pg/ml417 pg/ml418 pg/ml419 pg/ml420 pg/ml421 pg/ml422 pg/ml423 pg/ml
424 pg/ml425 pg/ml426 pg/ml427 pg/ml428 pg/ml429 pg/ml430 pg/ml431 pg/ml
432 pg/ml433 pg/ml434 pg/ml435 pg/ml436 pg/ml437 pg/ml438 pg/ml439 pg/ml
440 pg/ml441 pg/ml442 pg/ml443 pg/ml444 pg/ml445 pg/ml446 pg/ml447 pg/ml
448 pg/ml449 pg/ml450 pg/ml451 pg/ml452 pg/ml453 pg/ml454 pg/ml455 pg/ml
456 pg/ml457 pg/ml458 pg/ml459 pg/ml460 pg/ml461 pg/ml462 pg/ml463 pg/ml
464 pg/ml465 pg/ml466 pg/ml467 pg/ml468 pg/ml469 pg/ml470 pg/ml471 pg/ml
472 pg/ml473 pg/ml474 pg/ml475 pg/ml476 pg/ml477 pg/ml478 pg/ml479 pg/ml
480 pg/ml481 pg/ml482 pg/ml483 pg/ml484 pg/ml485 pg/ml486 pg/ml487 pg/ml
488 pg/ml489 pg/ml490 pg/ml491 pg/ml492 pg/ml493 pg/ml494 pg/ml495 pg/ml
496 pg/ml497 pg/ml498 pg/ml499 pg/ml500 pg/ml501 pg/ml502 pg/ml503 pg/ml
504 pg/ml505 pg/ml506 pg/ml507 pg/ml508 pg/ml509 pg/ml510 pg/ml511 pg/ml
512 pg/ml513 pg/ml514 pg/ml515 pg/ml516 pg/ml517 pg/ml518 pg/ml519 pg/ml
520 pg/ml521 pg/ml522 pg/ml523 pg/ml524 pg/ml525 pg/ml526 pg/ml527 pg/ml
528 pg/ml529 pg/ml530 pg/ml531 pg/ml532 pg/ml533 pg/ml534 pg/ml535 pg/ml
536 pg/ml537 pg/ml538 pg/ml539 pg/ml540 pg/ml541 pg/ml542 pg/ml543 pg/ml
544 pg/ml545 pg/ml546 pg/ml547 pg/ml548 pg/ml549 pg/ml550 pg/ml551 pg/ml
552 pg/ml553 pg/ml554 pg/ml555 pg/ml556 pg/ml557 pg/ml558 pg/ml559 pg/ml
560 pg/ml561 pg/ml562 pg/ml563 pg/ml564 pg/ml565 pg/ml566 pg/ml567 pg/ml
568 pg/ml569 pg/ml570 pg/ml571 pg/ml572 pg/ml573 pg/ml574 pg/ml575 pg/ml
576 pg/ml577 pg/ml578 pg/ml579 pg/ml580 pg/ml581 pg/ml582 pg/ml583 pg/ml
584 pg/ml585 pg/ml586 pg/ml587 pg/ml588 pg/ml589 pg/ml590 pg/ml591 pg/ml
592 pg/ml593 pg/ml594 pg/ml595 pg/ml596 pg/ml597 pg/ml598 pg/ml599 pg/ml
600 pg/ml601 pg/ml602 pg/ml603 pg/ml604 pg/ml605 pg/ml606 pg/ml607 pg/ml
608 pg/ml609 pg/ml610 pg/ml611 pg/ml612 pg/ml613 pg/ml614 pg/ml615 pg/ml
616 pg/ml617 pg/ml618 pg/ml619 pg/ml620 pg/ml621 pg/ml622 pg/ml623 pg/ml
624 pg/ml625 pg/ml626 pg/ml627 pg/ml628 pg/ml629 pg/ml630 pg/ml631 pg/ml
632 pg/ml633 pg/ml634 pg/ml635 pg/ml636 pg/ml637 pg/ml638 pg/ml639 pg/ml
640 pg/ml641 pg/ml642 pg/ml643 pg/ml644 pg/ml645 pg/ml646 pg/ml647 pg/ml
648 pg/ml649 pg/ml650 pg/ml651 pg/ml652 pg/ml653 pg/ml654 pg/ml655 pg/ml
656 pg/ml657 pg/ml658 pg/ml659 pg/ml660 pg/ml661 pg/ml662 pg/ml663 pg/ml
664 pg/ml665 pg/ml666 pg/ml667 pg/ml668 pg/ml669 pg/ml670 pg/ml671 pg/ml
672 pg/ml673 pg/ml674 pg/ml675 pg/ml676 pg/ml677 pg/ml678 pg/ml679 pg/ml
680 pg/ml681 pg/ml682 pg/ml683 pg/ml684 pg/ml685 pg/ml686 pg/ml687 pg/ml
688 pg/ml689 pg/ml690 pg/ml691 pg/ml692 pg/ml693 pg/ml694 pg/ml695 pg/ml
696 pg/ml697 pg/ml698 pg/ml699 pg/ml700 pg/ml701 pg/ml702 pg/ml703 pg/ml
704 pg/ml705 pg/ml706 pg/ml707 pg/ml708 pg/ml709 pg/ml710 pg/ml711 pg/ml
712 pg/ml713 pg/ml714 pg/ml715 pg/ml716 pg/ml717 pg/ml718 pg/ml719 pg/ml
720 pg/ml721 pg/ml722 pg/ml723 pg/ml724 pg/ml725 pg/ml726 pg/ml727 pg/ml
728 pg/ml729 pg/ml730 pg/ml731 pg/ml732 pg/ml733 pg/ml734 pg/ml735 pg/ml
736 pg/ml737 pg/ml738 pg/ml739 pg/ml740 pg/ml741 pg/ml742 pg/ml743 pg/ml
744 pg/ml745 pg/ml746 pg/ml747 pg/ml748 pg/ml749 pg/ml750 pg/ml751 pg/ml
752 pg/ml753 pg/ml754 pg/ml755 pg/ml756 pg/ml757 pg/ml758 pg/ml759 pg/ml
760 pg/ml761 pg/ml762 pg/ml763 pg/ml764 pg/ml765 pg/ml766 pg/ml767 pg/ml
768 pg/ml769 pg/ml770 pg/ml771 pg/ml772 pg/ml773 pg/ml774 pg/ml775 pg/ml
776 pg/ml777 pg/ml778 pg/ml779 pg/ml780 pg/ml781 pg/ml782 pg/ml783 pg/ml
784 pg/ml785 pg/ml786 pg/ml787 pg/ml788 pg/ml789 pg/ml790 pg/ml791 pg/ml
792 pg/ml793 pg/ml794 pg/ml795 pg/ml796 pg/ml797 pg/ml798 pg/ml799 pg/ml
800 pg/ml801 pg/ml802 pg/ml803 pg/ml804 pg/ml805 pg/ml806 pg/ml807 pg/ml
808 pg/ml809 pg/ml810 pg/ml811 pg/ml812 pg/ml813 pg/ml814 pg/ml815 pg/ml
816 pg/ml817 pg/ml818 pg/ml819 pg/ml820 pg/ml821 pg/ml822 pg/ml823 pg/ml
824 pg/ml825 pg/ml826 pg/ml827 pg/ml828 pg/ml829 pg/ml830 pg/ml831 pg/ml
832 pg/ml833 pg/ml834 pg/ml835 pg/ml    
Medically reviewed by our Medical staff on 03/05/2022

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