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Normal TIBC level in the blood

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Normal TIBC level in the blood

What is the normal TIBC level in the blood?

Adults: 250 - 460 µg/dL
Children from 0 to 3 months old: 155 - 330 µg/dL
Children from 3 to 12 months old: 150 - 450 µg/dL
Children from 1 to 4 years old: 160 - 420 µg/dL
Children from 4 to 18 years old: 250 - 420 µg/dL

In the International System of Units (SI), TIBC is measured in g/L. The normal TIBC ranges in the SI are:

Adults 2.50 - 4.60 g/L
Children from 0 to 3 months old 1.55 - 3.30 g/L
Children from 3 to 12 months old 1.50 - 4.50 g/L
Children from 1 to 4 years old 1.60 - 4.20 g/L
Children from de 4 to 18 years old: 2.50 - 4.20 g/L

Why normal levels can differ across different labs?

Each laboratory must establish its own normal ranges for TIBC in the blood. These ranges depend on the makeup of the local population, the technologies used and the accuracy of the measurement. There may be also slight differences in the normal levels according to age, gender, race or ethnic origin, geographic region, diet, type of sample and other relevant status.

Your doctor will study the results along with your medical record, screenings, physical condition, symptoms and any other relevant information about your situation.

¿What is TIBC?

TIBC is the acronym of Total Iron Binding Capacity. TIBC is a diagnostic screening test that expresses the amount of iron that can be bound to transferrin. Transferrin is the protein that carries iron trough the blood.

When a blood assay is performed is cheaper and easier to measure TIBC than to measure transferrin directly. TIBC is an indirect form to measure the transferrin level in the blood.

Each transferrin molecule can bind to two atoms of ferric iron (Fe3+). It means that transferrin has the capacity to transport approximately from 1.40 to 1.49 mg of iron per gram of transferrin present in the blood.

If TIBC values are known, the transferrin level can be estimated with the following formulas.

  • Transferrin (mg/dL) = 0.8 x TIBC (µg of iron/dL) – 43
  • Transferrin (mg/dL) = 0.7 x TIBC (µg of iron/dL)

What is TIBC test used for?

TIBC (Total Iron Binding Capacity) assay is usually performed to study anemia. It gives additional information to iron or ferritin level in the blood. In addition, it is also interesting to know the transferrin saturation for a better diagnosis.

TIBC is used to differentiate iron-deficiency anemia from anemia of chronic disease. In case of iron-deficiency anemia TIBC will be higher than normal. In anemia of chronic disease TIBC will be lower than normal.

TIBC test is also useful to detect hemochromatosis, a disease that provokes accumulation of iron in different organs. In case of hemochromatosis, TIBC will be lower than normal and the percentage % of transferrin saturation will be high.

Where can I find more information about TIBC level in the blood?

You can visit our pages about:

Which values are considered a normal TIBC level in the blood?

The following values are considered to be normal values:

IMPORTANT: These levels are expressed in µg/dL. They are an example of a healthy woman of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

TIBC
Status
Normality
250 µg/dL251 µg/dL252 µg/dL253 µg/dL254 µg/dL255 µg/dL256 µg/dL257 µg/dL
258 µg/dL259 µg/dL260 µg/dL261 µg/dL262 µg/dL263 µg/dL264 µg/dL265 µg/dL
266 µg/dL267 µg/dL268 µg/dL269 µg/dL270 µg/dL271 µg/dL272 µg/dL273 µg/dL
274 µg/dL275 µg/dL276 µg/dL277 µg/dL278 µg/dL279 µg/dL280 µg/dL281 µg/dL
282 µg/dL283 µg/dL284 µg/dL285 µg/dL286 µg/dL287 µg/dL288 µg/dL289 µg/dL
290 µg/dL291 µg/dL292 µg/dL293 µg/dL294 µg/dL295 µg/dL296 µg/dL297 µg/dL
298 µg/dL299 µg/dL300 µg/dL301 µg/dL302 µg/dL303 µg/dL304 µg/dL305 µg/dL
306 µg/dL307 µg/dL308 µg/dL309 µg/dL310 µg/dL311 µg/dL312 µg/dL313 µg/dL
314 µg/dL315 µg/dL316 µg/dL317 µg/dL318 µg/dL319 µg/dL320 µg/dL321 µg/dL
322 µg/dL323 µg/dL324 µg/dL325 µg/dL326 µg/dL327 µg/dL328 µg/dL329 µg/dL
330 µg/dL331 µg/dL332 µg/dL333 µg/dL334 µg/dL335 µg/dL336 µg/dL337 µg/dL
338 µg/dL339 µg/dL340 µg/dL341 µg/dL342 µg/dL343 µg/dL344 µg/dL345 µg/dL
346 µg/dL347 µg/dL348 µg/dL349 µg/dL350 µg/dL351 µg/dL352 µg/dL353 µg/dL
354 µg/dL355 µg/dL356 µg/dL357 µg/dL358 µg/dL359 µg/dL360 µg/dL361 µg/dL
362 µg/dL363 µg/dL364 µg/dL365 µg/dL366 µg/dL367 µg/dL368 µg/dL369 µg/dL
370 µg/dL371 µg/dL372 µg/dL373 µg/dL374 µg/dL375 µg/dL376 µg/dL377 µg/dL
378 µg/dL379 µg/dL380 µg/dL381 µg/dL382 µg/dL383 µg/dL384 µg/dL385 µg/dL
386 µg/dL387 µg/dL388 µg/dL389 µg/dL390 µg/dL391 µg/dL392 µg/dL393 µg/dL
394 µg/dL395 µg/dL396 µg/dL397 µg/dL398 µg/dL399 µg/dL400 µg/dL401 µg/dL
402 µg/dL403 µg/dL404 µg/dL405 µg/dL406 µg/dL407 µg/dL408 µg/dL409 µg/dL
410 µg/dL411 µg/dL412 µg/dL413 µg/dL414 µg/dL415 µg/dL416 µg/dL417 µg/dL
418 µg/dL419 µg/dL420 µg/dL421 µg/dL422 µg/dL423 µg/dL424 µg/dL425 µg/dL
426 µg/dL427 µg/dL428 µg/dL429 µg/dL430 µg/dL431 µg/dL432 µg/dL433 µg/dL
434 µg/dL435 µg/dL436 µg/dL437 µg/dL438 µg/dL439 µg/dL440 µg/dL441 µg/dL
442 µg/dL443 µg/dL444 µg/dL445 µg/dL446 µg/dL447 µg/dL448 µg/dL449 µg/dL
450 µg/dL451 µg/dL452 µg/dL453 µg/dL454 µg/dL455 µg/dL456 µg/dL457 µg/dL
458 µg/dL459 µg/dL460 µg/dL     
foto de Dr. Javier Muga Bustamante
Written by

Dr. Javier Muga Bustamante

Last update: 22/04/2020

Bibliography

  • Tietz. Fundamentals of Clinical Chemistry. Carl A. Burtis, Edward R. Ashwood, David E. Bruns, Barbara G. Sawyer. WB Saunders Company, 2008. Pag 302. ISBN: 978-0-7216-3865-2.
  • Laboratory tests and diagnostic procedures with nursing diagnoses (8th ed), Jane Vincent Corbett, Angela Denise Banks, ISBN: 978-0-13-237332-6, Pag. 39.
  • Serum iron, ferritin, transferrin, total iron binding capacity, hs-CRP, LDL cholesterol and magnesium in children; new reference intervals using the Dade Dimension Clinical Chemistry System. Disponible en: https://www.ncbi.nlm.nih.gov
  • (PDF) Total Iron Binding Capacity and Transferrin Concentration in the Assessment of Iron Status. Available from. Disponible en: https://www.researchgate.net

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