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Low (AST) Aspartate Aminotransferase level in the blood

Blood test
Low (AST) Aspartate Aminotransferase level in the blood
Last update: 25/03/2020

What is low AST level in the blood called?

  • AST Hypotransaminasemia

What is the normal level of AST in the blood?

If you need to know which are the AST reference ranges or you require more information about the role of AST in the blood, you can visit normal AST level in the blood

What does a low AST level in the blood mean?

A low AST (Aspartate aminotransferase) level in the blood, formerly named glutamate oxaloacetate transaminase (GOT), is not common and, in general, it is not a matter for concern.

  • Mild AST hypotransaminasemia (0 - 5 U/L in adults):

    The AST level in the blood is a bit low. Low AST values are usually a positive sign and they are not associated with any medical condition or disease.

    Only in case you have diabetes or you follow an unbalanced diet, it is advisable to visit your doctor.

Which factors can reduce the AST level in the blood?

To suffer a particular health situation can reduce your AST level in the blood:

  • Vitamin deficiency
  • Pregnancy

Which diseases can reduce your AST level in the blood?

The following diseases can explain an AST level in the blood lower than normal:

What can I do to increase the AST level in the blood?

A low AST level in the blood can be due to a vitamin deficiency. The main vitamin involved is vitamin B6 (pyridoxine). You can increase your vitamin B6 intake by taking:

  • Nuts: Pistachios, hazelnuts, walnuts.
  • Meat: veal or chicken liver, turkey.
  • Fish: Salmon, tuna.

Where can I find more information about AST in the blood?

You can visit our pages about:

Which values are considered a low AST level in the blood?

The following values are considered to be below the normal range:

IMPORTANT: These levels are expressed in U/L. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

AST Aspartate Aminotransferase
Mild AST hypotransaminasemia
4 U/L3 U/L2 U/L1 U/L0 U/L   
Medically reviewed by Javier Muga Bustamante Ph.D. on 25/03/2020


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  • Severity grading in drug induced liver injury. U.S. National Library of Medicine. Available on:

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