Blood test

Low activated partial thromboplastin time (aPTT) in a blood test

Blood test
>
Low activated partial thromboplastin time (aPTT) in a blood test
Last update: 21/05/2021

What is low activated partial thromboplastin time (aPTT) in a blood test called?

  • Low activated partial thromboplastin time (aPTT)

What is the normal activated partial thromboplastin time (aPTT) in a blood test?

If you need to know which are the activated partial thromboplastin time (aPTT) reference ranges or you require more information about activated partial thromboplastin time (aPTT) in a blood test, you can visit normal activated partial thromboplastin time (aPTT) in a blood test.

What does a low activated partial thromboplastin time (aPTT) in a blood test mean?

A low activated partial thromboplastin time (aPTT) show that blood is clotting faster than normal and that increases the risk to develop a blood clot.

Shortened activated partial thromboplastin time (aPTT) occurs in:

  • Extensive cancer, except when the liver is involved.
  • Immediately after acute hemorrhage.
  • Very early stages of DIC (later the aPTT increases).

A low activated partial thromboplastin time (aPTT) is rare. It is recommended to perform a new test again to exclude the possibility of heparin contamination or any other measurement error.

  • Mild activated partial thromboplastin time (aPTT) decrease (< 20 seconds in adults):

    An activated partial thromboplastin time (aPTT) lower than the control sample is not diagnostically significant, but it may be a clue reflecting hypercoagulability.

    Some studies suggest that a low aPTT time increase the possibility of thrombosis or. This may be because a low aPTT time is seen in case of extensive cancer or severe bleeding.

Which factors can reduce the activated partial thromboplastin time (aPTT) in a blood test?

There are some circumstances and drugs than can reduce your activated partial thromboplastin time (aPTT) in a blood test:

  • Vitamin C excess intake
  • Drugs
    • Oral Contraceptives
      • Estrogens

Which diseases can reduce your activated partial thromboplastin time (aPTT) in a blood test?

The most common diseases why the activated partial thromboplastin time (aPTT) can be lower than normal are:

  • Ovarian cancer
  • Pancreatic cancer
  • Colorectal cancer

What can I do to increase the activated partial thromboplastin time (aPTT) in a blood test?

If your doctor considers it appropriate he may prescribe you anticoagulant therapy, such as heparin therapy that prevent thrombosis and increase activated partial thromboplastin time (aPTT).

Where can I find more information about activated partial thromboplastin time (aPTT) in a blood test?

You can visit our pages about:

Which values are considered a low activated partial thromboplastin time (aPTT) in a blood test?

The following values are considered to be above the normal range:

IMPORTANT: These levels are expressed in seconds. They are an example of a healthy man/woman of about 40 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Activated partial thromboplastin time (aPTT)
Mild activated partial thromboplastin time (aPTT) decrease
19.9 s19.8 s19.7 s19.6 s19.5 s19.4 s19.3 s19.2 s
19.1 s19 s18.9 s18.8 s18.7 s18.6 s18.5 s18.4 s
18.3 s18.2 s18.1 s18 s17.9 s17.8 s17.7 s17.6 s
17.5 s17.4 s17.3 s17.2 s17.1 s17 s16.9 s16.8 s
16.7 s16.6 s16.5 s16.4 s16.3 s16.2 s16.1 s16 s
15.9 s15.8 s15.7 s15.6 s15.5 s15.4 s15.3 s15.2 s
15.1 s15 s14.9 s14.8 s14.7 s14.6 s14.5 s14.4 s
14.3 s14.2 s14.1 s14 s13.9 s13.8 s13.7 s13.6 s
13.5 s13.4 s13.3 s13.2 s13.1 s13 s12.9 s12.8 s
12.7 s12.6 s12.5 s12.4 s12.3 s12.2 s12.1 s12 s
11.9 s11.8 s11.7 s11.6 s11.5 s11.4 s11.3 s11.2 s
11.1 s11 s10.9 s10.8 s10.7 s10.6 s10.5 s10.4 s
10.3 s10.2 s10.1 s10 s    
Medically reviewed by our Medical staff on 21/05/2021

Bibliography

  • Concise Book of Medical Laboratory Technology Methods and Interpretations. 2nd edition. 2015. Ramnik Sood. ISBN 978-93-5152-333-8. Pag 293.
  • The Gale Encyclopedia of Nursing & Allied Health. 2002. Kristine Krapp. ISBN 0-7876-4934-1. Pag 517.
  • A Manual of Laboratory and Diagnostic Test. 9th edition. Frances Fischbach. Marshall B. Dunning III. 2014. Pag 156. ISBN-10: 1451190891.
  • Laboratory tests and diagnostic procedures with nursing diagnoses (8th ed), Jane Vincent Corbett, Angela Denise Banks, ISBN: 978-0-13-237332-6, Pag. 310.
  • Essentials of Medical Laboratory Practice. Constance L. Lieseke, Elizabeth A. Zeibig. 2012. ISBN: 978-0-8036-1899-2 Pag: 323.

Show more

Rating Overview

Share your thoughts about this content
Poor
Excellent

E-mail (Optional):
Add a review