Blood test

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Low LDH level in the blood

Blood test
Low LDH level in the blood
Last update: 24/11/2020

What is low total LDH level in the blood called?

  • LDH low

What is the normal LDH level in the blood?

If you need to know which are the LDH reference ranges or you require more information about the role of LDH in the blood, you can visit normal LDH level in the blood

What does a low total LDH level in the blood mean?

A low level of LDH (lactate dehydrogenase) in the blood is not common, it is not clinically significant and it is not usually a matter for concern.

Sometimes, LDH is used to monitor a cancer treatment and if LDH values decrease, it is a positive sign of the treatment.

LDH blood values are usually given in UI/l but sometimes you can see these values in µkat/L following the International System of Units (SI). In case your values are in µkat/L you can convert them using this tool:


A low LDH blood level means:

  • Moderate LDH decrease (< 130 UI/l in adults):

    LDH level is below the normal range and it may be due to an excessive vitamin C intake or due to a drug interference.

    However, there are some people with a genetic mutation with a low permanent LDH level in the blood. There are two genetic disorders:

    • Lactate dehydrogenase-A deficiency (glycogen storage disease XI). People with this disorder suffer from fatigue, cramps and muscle pain doing exercise.
    • Lactate dehydrogenase-B deficiency: People with this disorder usually have no symptoms.

Which factors can reduce the LDH level in the blood?

Some particular health situation or drugs may reduce your LDH level in the blood:

  • Vitamin C excess intake
  • Drugs

Which diseases can reduce your LDH level in the blood?

The following diseases can explain a LDH level in the blood lower than normal:

  • Lactate dehydrogenase-A deficiency (glycogen storage disease XI)
  • Lactate dehydrogenase-B deficiency

What can I do to increase the LDH level in the blood?

A low level of LDH in the blood may be due to an excessive intake of vitamin C. For that reason, you may reduce the vitamin C intake if this is the cause. There are rich in vitamin C and you should reduce the intake of oranges, tangerines, peppers, broccoli, strawberries, melon or kiwis.

Where can I find more information about LDH level in the blood?

You can visit our pages about:

Which values are considered a low LDH level in the blood?

The following values are considered to be above the normal range:

IMPORTANT: These levels are expressed in UI/l. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

Lactate dehydrogenase (LDH)
Moderate LDH decrease
129 UI/l128 UI/l127 UI/l126 UI/l125 UI/l124 UI/l123 UI/l122 UI/l
121 UI/l120 UI/l119 UI/l118 UI/l117 UI/l116 UI/l115 UI/l114 UI/l
113 UI/l112 UI/l111 UI/l110 UI/l109 UI/l108 UI/l107 UI/l106 UI/l
105 UI/l104 UI/l103 UI/l102 UI/l101 UI/l100 UI/l99 UI/l98 UI/l
97 UI/l96 UI/l95 UI/l94 UI/l93 UI/l92 UI/l91 UI/l90 UI/l
89 UI/l88 UI/l87 UI/l86 UI/l85 UI/l84 UI/l83 UI/l82 UI/l
81 UI/l80 UI/l79 UI/l78 UI/l77 UI/l76 UI/l75 UI/l74 UI/l
73 UI/l72 UI/l71 UI/l70 UI/l69 UI/l68 UI/l67 UI/l66 UI/l
65 UI/l64 UI/l63 UI/l62 UI/l61 UI/l60 UI/l59 UI/l58 UI/l
57 UI/l56 UI/l55 UI/l54 UI/l53 UI/l52 UI/l51 UI/l50 UI/l
49 UI/l48 UI/l47 UI/l46 UI/l45 UI/l44 UI/l43 UI/l42 UI/l
41 UI/l40 UI/l39 UI/l38 UI/l37 UI/l36 UI/l35 UI/l34 UI/l
33 UI/l32 UI/l31 UI/l30 UI/l29 UI/l28 UI/l27 UI/l26 UI/l
25 UI/l24 UI/l23 UI/l22 UI/l21 UI/l20 UI/l19 UI/l18 UI/l
17 UI/l16 UI/l15 UI/l14 UI/l13 UI/l12 UI/l11 UI/l10 UI/l
9 UI/l8 UI/l7 UI/l6 UI/l5 UI/l4 UI/l3 UI/l2 UI/l
1 UI/l0 UI/l      
Medically reviewed by our Medical staff on 24/11/2020


  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 538.
  • Tietz. Fundamentals of Clinical Chemistry. Carl A. Burtis, Edward R. Ashwood, David E. Bruns, Barbara G. Sawyer. WB Saunders Company, 2008. Pag 321. ISBN: 978-0-7216-3865-2.
  • Laboratory tests and diagnostic procedures with nursing diagnoses (8th ed), Jane Vincent Corbett, Angela Denise Banks, ISBN: 978-0-13-237332-6, Pag. 285.

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