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High Alpha-Fetoprotein AFP in a blood test

Blood test
High Alpha-Fetoprotein AFP in a blood test
Last update: 06/07/2021

What is a high alpha-fetoprotein AFP in a blood test called?

  • Alpha-fetoprotein high

What is the normal alpha-fetoprotein AFP in a blood test?

If you need to know which are the alpha-fetoprotein AFP reference ranges or you require more information about alpha-fetoprotein AFP in a blood test, you can visit normal alpha-fetoprotein AFP in a blood test.

What does a high alpha-fetoprotein AFP mean?

Some disorders and diseases may elevate the Alpha-Fetoprotein (α-Fetoprotein or AFP) in a blood test, such as some types of cancer or benign liver diseases such as hepatitis, cirrhosis or cholestasis.

If your doctor has ordered the alpha-fetoprotein blood test and you are not a pregnant woman is usually because he suspects that you can suffer from liver or testicular cancer, two types of cancer that elevated the presence of alpha-fetoprotein in the blood.

The alpha-fetoprotein blood test is also performed on pregnant women to detect congenital anomalies (birth defects). It is performed within the triple test during pregnancy and it has its own meaning. The content of this page is valid for non-pregnant people when the test is requested as a tumor marker.

  • Mild alpha-fetoprotein AFP increase (8.5 - 100 ng/ml in adults):

    The level of alpha-fetoprotein in the blood is a bit high. The alpha-fetoprotein blood test has a low specificity because there are many disorders, both benign and malignant, that may elevate the alpha-fetoprotein level in the blood.

    Therefore, your doctor will study your medical history, the complete blood test and all the information related to your case to explain you the possible reason for that increase.

  • Moderate alpha-fetoprotein AFP increase (100 - 350 ng/ml in adults):

    A moderate alpha-fetoprotein increase in a non-pregnant woman is sometimes related to a primary liver cancer (hepatocellular carcinoma).

    Therefore, your doctor will tell you if it is necessary to perform additional tests for a proper diagnosis.

    A moderate alpha-fetoprotein increase may due also to a benign liver disease such as cirrhosis or hepatitis.

  • Severe alpha-fetoprotein AFP increase (> 350 ng/ml in adults):

    The probability of suffering a liver cancer in a non-pregnant woman with a severe alpha-fetoprotein increase in the blood is very high.

    Concentrations over 1000 ng/mL usually are indication of hepatocellular carcinoma (liver cancer).

Which factors can raise the alpha-fetoprotein AFP in a blood test?

The main circumstance that may raise the alpha-fetoprotein in a blood test is:

  • Pregnancy

Which diseases can raise your alpha-fetoprotein AFP in a blood test?

The most common diseases why the alpha-fetoprotein AFP may be higher than normal are:

What can I do to lower the alpha-fetoprotein AFP in a blood test?

The alpha-fetoprotein blood test is usually used a tumor marker. For that reason, to reduce the concentrations of alpha-fetoprotein in the blood the best method is to treat the underlying disease that is causing it, usually a cancer.

Where can I find more information about alpha-fetoprotein AFP in a blood test?

You can visit our pages about:

Which values are considered a high alpha-fetoprotein AFP in a blood test?

The following values are considered to be above the normal range:

IMPORTANT: These levels are expressed in ng/ml. They are an example of a healthy adult of about 40 years old with no known disease, not taking any medication and not pregnant if you are a woman. The ranges can be different depending on the laboratory or on your personal circumstances.

Alpha-fetoprotein AFP
Mild alpha-protein AFP increase
8.6 ng/ml8.7 ng/ml8.8 ng/ml8.9 ng/ml9 ng/ml9.1 ng/ml9.2 ng/ml9.3 ng/ml
9.4 ng/ml9.5 ng/ml9.6 ng/ml9.7 ng/ml9.8 ng/ml9.9 ng/ml10 ng/ml10.1 ng/ml
10.2 ng/ml10.3 ng/ml10.4 ng/ml10.5 ng/ml10.6 ng/ml10.7 ng/ml10.8 ng/ml10.9 ng/ml
11 ng/ml11.1 ng/ml11.2 ng/ml11.3 ng/ml11.4 ng/ml11.5 ng/ml11.6 ng/ml11.7 ng/ml
11.8 ng/ml11.9 ng/ml12 ng/ml12.1 ng/ml12.2 ng/ml12.3 ng/ml12.4 ng/ml12.5 ng/ml
12.6 ng/ml12.7 ng/ml12.8 ng/ml12.9 ng/ml13 ng/ml13.1 ng/ml13.2 ng/ml13.3 ng/ml
13.4 ng/ml13.5 ng/ml13.6 ng/ml13.7 ng/ml13.8 ng/ml13.9 ng/ml14 ng/ml14.1 ng/ml
14.2 ng/ml14.3 ng/ml14.4 ng/ml14.5 ng/ml14.6 ng/ml14.7 ng/ml14.8 ng/ml14.9 ng/ml
15 ng/ml15.1 ng/ml15.2 ng/ml15.3 ng/ml15.4 ng/ml15.5 ng/ml15.6 ng/ml15.7 ng/ml
15.8 ng/ml15.9 ng/ml16 ng/ml16.1 ng/ml16.2 ng/ml16.3 ng/ml16.4 ng/ml16.5 ng/ml
16.6 ng/ml16.7 ng/ml16.8 ng/ml16.9 ng/ml17 ng/ml17.1 ng/ml17.2 ng/ml17.3 ng/ml
17.4 ng/ml17.5 ng/ml17.6 ng/ml17.7 ng/ml17.8 ng/ml17.9 ng/ml18 ng/ml18.1 ng/ml
18.2 ng/ml18.3 ng/ml18.4 ng/ml18.5 ng/ml18.6 ng/ml18.7 ng/ml18.8 ng/ml18.9 ng/ml
19 ng/ml19.1 ng/ml19.2 ng/ml19.3 ng/ml19.4 ng/ml19.5 ng/ml19.6 ng/ml19.7 ng/ml
19.8 ng/ml19.9 ng/ml20 ng/ml20.1 ng/ml20.2 ng/ml20.3 ng/ml20.4 ng/ml20.5 ng/ml
20.6 ng/ml20.7 ng/ml20.8 ng/ml20.9 ng/ml21 ng/ml21.1 ng/ml21.2 ng/ml21.3 ng/ml
21.4 ng/ml21.5 ng/ml21.6 ng/ml21.7 ng/ml21.8 ng/ml21.9 ng/ml22 ng/ml22.1 ng/ml
22.2 ng/ml22.3 ng/ml22.4 ng/ml22.5 ng/ml22.6 ng/ml22.7 ng/ml22.8 ng/ml22.9 ng/ml
23 ng/ml23.1 ng/ml23.2 ng/ml23.3 ng/ml23.4 ng/ml23.5 ng/ml23.6 ng/ml23.7 ng/ml
23.8 ng/ml23.9 ng/ml24 ng/ml24.1 ng/ml24.2 ng/ml24.3 ng/ml24.4 ng/ml24.5 ng/ml
24.6 ng/ml24.7 ng/ml24.8 ng/ml24.9 ng/ml25 ng/ml25.1 ng/ml25.2 ng/ml25.3 ng/ml
25.4 ng/ml25.5 ng/ml25.6 ng/ml25.7 ng/ml25.8 ng/ml25.9 ng/ml26 ng/ml26.1 ng/ml
26.2 ng/ml26.3 ng/ml26.4 ng/ml26.5 ng/ml26.6 ng/ml26.7 ng/ml26.8 ng/ml26.9 ng/ml
27 ng/ml27.1 ng/ml27.2 ng/ml27.3 ng/ml27.4 ng/ml27.5 ng/ml27.6 ng/ml27.7 ng/ml
27.8 ng/ml27.9 ng/ml28 ng/ml28.1 ng/ml28.2 ng/ml28.3 ng/ml28.4 ng/ml28.5 ng/ml
28.6 ng/ml28.7 ng/ml28.8 ng/ml28.9 ng/ml29 ng/ml29.1 ng/ml29.2 ng/ml29.3 ng/ml
29.4 ng/ml29.5 ng/ml29.6 ng/ml29.7 ng/ml29.8 ng/ml29.9 ng/ml30 ng/ml30.1 ng/ml
30.2 ng/ml30.3 ng/ml30.4 ng/ml30.5 ng/ml30.6 ng/ml30.7 ng/ml30.8 ng/ml30.9 ng/ml
31 ng/ml31.1 ng/ml31.2 ng/ml31.3 ng/ml31.4 ng/ml31.5 ng/ml31.6 ng/ml31.7 ng/ml
31.8 ng/ml31.9 ng/ml32 ng/ml32.1 ng/ml32.2 ng/ml32.3 ng/ml32.4 ng/ml32.5 ng/ml
32.6 ng/ml32.7 ng/ml32.8 ng/ml32.9 ng/ml33 ng/ml33.1 ng/ml33.2 ng/ml33.3 ng/ml
33.4 ng/ml33.5 ng/ml33.6 ng/ml33.7 ng/ml33.8 ng/ml33.9 ng/ml34 ng/ml34.1 ng/ml
34.2 ng/ml34.3 ng/ml34.4 ng/ml34.5 ng/ml34.6 ng/ml34.7 ng/ml34.8 ng/ml34.9 ng/ml
35 ng/ml35.1 ng/ml35.2 ng/ml35.3 ng/ml35.4 ng/ml35.5 ng/ml35.6 ng/ml35.7 ng/ml
35.8 ng/ml35.9 ng/ml36 ng/ml36.1 ng/ml36.2 ng/ml36.3 ng/ml36.4 ng/ml36.5 ng/ml
36.6 ng/ml36.7 ng/ml36.8 ng/ml36.9 ng/ml37 ng/ml37.1 ng/ml37.2 ng/ml37.3 ng/ml
37.4 ng/ml37.5 ng/ml37.6 ng/ml37.7 ng/ml37.8 ng/ml37.9 ng/ml38 ng/ml38.1 ng/ml
38.2 ng/ml38.3 ng/ml38.4 ng/ml38.5 ng/ml38.6 ng/ml38.7 ng/ml38.8 ng/ml38.9 ng/ml
39 ng/ml39.1 ng/ml39.2 ng/ml39.3 ng/ml39.4 ng/ml39.5 ng/ml39.6 ng/ml39.7 ng/ml
39.8 ng/ml39.9 ng/ml40 ng/ml40.1 ng/ml40.2 ng/ml40.3 ng/ml40.4 ng/ml40.5 ng/ml
40.6 ng/ml40.7 ng/ml40.8 ng/ml40.9 ng/ml41 ng/ml41.1 ng/ml41.2 ng/ml41.3 ng/ml
41.4 ng/ml41.5 ng/ml41.6 ng/ml41.7 ng/ml41.8 ng/ml41.9 ng/ml42 ng/ml42.1 ng/ml
42.2 ng/ml42.3 ng/ml42.4 ng/ml42.5 ng/ml42.6 ng/ml42.7 ng/ml42.8 ng/ml42.9 ng/ml
43 ng/ml43.1 ng/ml43.2 ng/ml43.3 ng/ml43.4 ng/ml43.5 ng/ml43.6 ng/ml43.7 ng/ml
43.8 ng/ml43.9 ng/ml44 ng/ml44.1 ng/ml44.2 ng/ml44.3 ng/ml44.4 ng/ml44.5 ng/ml
44.6 ng/ml44.7 ng/ml44.8 ng/ml44.9 ng/ml45 ng/ml45.1 ng/ml45.2 ng/ml45.3 ng/ml
45.4 ng/ml45.5 ng/ml45.6 ng/ml45.7 ng/ml45.8 ng/ml45.9 ng/ml46 ng/ml46.1 ng/ml
46.2 ng/ml46.3 ng/ml46.4 ng/ml46.5 ng/ml46.6 ng/ml46.7 ng/ml46.8 ng/ml46.9 ng/ml
47 ng/ml47.1 ng/ml47.2 ng/ml47.3 ng/ml47.4 ng/ml47.5 ng/ml47.6 ng/ml47.7 ng/ml
47.8 ng/ml47.9 ng/ml48 ng/ml48.1 ng/ml48.2 ng/ml48.3 ng/ml48.4 ng/ml48.5 ng/ml
48.6 ng/ml48.7 ng/ml48.8 ng/ml48.9 ng/ml49 ng/ml49.1 ng/ml49.2 ng/ml49.3 ng/ml
49.4 ng/ml49.5 ng/ml49.6 ng/ml49.7 ng/ml49.8 ng/ml49.9 ng/ml50 ng/ml50.1 ng/ml
50.2 ng/ml50.3 ng/ml50.4 ng/ml50.5 ng/ml50.6 ng/ml50.7 ng/ml50.8 ng/ml50.9 ng/ml
51 ng/ml51.1 ng/ml51.2 ng/ml51.3 ng/ml51.4 ng/ml51.5 ng/ml51.6 ng/ml51.7 ng/ml
51.8 ng/ml51.9 ng/ml52 ng/ml52.1 ng/ml52.2 ng/ml52.3 ng/ml52.4 ng/ml52.5 ng/ml
52.6 ng/ml52.7 ng/ml52.8 ng/ml52.9 ng/ml53 ng/ml53.1 ng/ml53.2 ng/ml53.3 ng/ml
53.4 ng/ml53.5 ng/ml53.6 ng/ml53.7 ng/ml53.8 ng/ml53.9 ng/ml54 ng/ml54.1 ng/ml
54.2 ng/ml54.3 ng/ml54.4 ng/ml54.5 ng/ml54.6 ng/ml54.7 ng/ml54.8 ng/ml54.9 ng/ml
55 ng/ml55.1 ng/ml55.2 ng/ml55.3 ng/ml55.4 ng/ml55.5 ng/ml55.6 ng/ml55.7 ng/ml
55.8 ng/ml55.9 ng/ml56 ng/ml56.1 ng/ml56.2 ng/ml56.3 ng/ml56.4 ng/ml56.5 ng/ml
56.6 ng/ml56.7 ng/ml56.8 ng/ml56.9 ng/ml57 ng/ml57.1 ng/ml57.2 ng/ml57.3 ng/ml
57.4 ng/ml57.5 ng/ml57.6 ng/ml57.7 ng/ml57.8 ng/ml57.9 ng/ml58 ng/ml58.1 ng/ml
58.2 ng/ml58.3 ng/ml58.4 ng/ml58.5 ng/ml58.6 ng/ml58.7 ng/ml58.8 ng/ml58.9 ng/ml
59 ng/ml59.1 ng/ml59.2 ng/ml59.3 ng/ml59.4 ng/ml59.5 ng/ml59.6 ng/ml59.7 ng/ml
59.8 ng/ml59.9 ng/ml60 ng/ml60.1 ng/ml60.2 ng/ml60.3 ng/ml60.4 ng/ml60.5 ng/ml
60.6 ng/ml60.7 ng/ml60.8 ng/ml60.9 ng/ml61 ng/ml61.1 ng/ml61.2 ng/ml61.3 ng/ml
61.4 ng/ml61.5 ng/ml61.6 ng/ml61.7 ng/ml61.8 ng/ml61.9 ng/ml62 ng/ml62.1 ng/ml
62.2 ng/ml62.3 ng/ml62.4 ng/ml62.5 ng/ml62.6 ng/ml62.7 ng/ml62.8 ng/ml62.9 ng/ml
Medically reviewed by our Medical staff on 06/07/2021


  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 683.
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