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High TSH level in the blood

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High TSH level in the blood
Last update: 22/10/2020

What is high level of total TSH (thyroid-stimulating hormone) in the blood called?

  • TSH High

What is the normal TSH level in the blood?

If you need to know which are the TSH reference ranges or you require more information about the role of TSH in the blood, you can visit normal TSH level in the blood

What does a high total TSH level in the blood mean?

A TSH (thyroid-stimulating hormone) level in the blood higher than normal range may be a sign of primary hypothyroidism, a situation where the thyroid gland fails to produce enough thyroid hormones. Thyroid hormones T3 (triiodothyronine) and T4 (thyroxine) will be lower than normal.

TSH (thyroid-stimulating hormone) is also called thyrotropin or thyrotropic hormone.

In the International System of Units (SI), TSH in the blood is measured in mU/L. The numeric values in this case are the same in µUI/ml or in mU/L.

High TSH blood levels mean:

  • Mild TSH increase (4 - 10 µUI/ml in adults):

    The TSH level in the blood is a bit high. It is necessary to study the T3 and T4 values.

    If T4 values are in the normal range it is usually due to subclinical hypothyroidism and no symptom will be present.

    This situation should be under periodical surveillance to detect a possible increase in the TSH levels. In children and women who are trying to conceive it may be adequate to start a treatment.

  • Marked TSH increase (10 - 100 µUI/ml in adults):

    The TSH level in the blood is very high and it may be a sign of suffering from hypothyroidism. If T4 hormone level is also below the normal range, hypothyroidism is conclusive.

    The main symptoms of hypothyroidism are fatigue, weight gain, constipation, drowsiness and menstrual disorders.

    You should visit your doctor. He will probably will give you a treatment with levothyroxine (a manufactured form of the thyroid hormone thyroxine T4).

  • Severe TSH increase (> 100 µUI/ in adults):

    The TSH levels are well above the normal range and it is likely probably a problem related to the thyroid hormones.

    You must visit a doctor as soon as possible to avoid serious health problems such as a myxedema coma.

Which factors can raise the TSH level in the blood?

There are some health circumstances or drugs than can raise your TSH level in the blood:

  • Thyroid ablation
  • Iodine deficiency
  • Overweight
  • Tobacco
  • Drugs
    • Antiarrhythmic agents
      • Amiodarone
    • Antiemetic
      • Domperidone
      • Metoclopramide
    • Antiepileptic drugs
      • Carbamazepine
      • Phenobarbital
    • Antihypertensives
      • Pyrimidine
    • Antithyroid agent
      • Carbimazole
      • Thiamazole
      • Propylthiouracil
    • Interferon
    • Lithium

Which diseases can raise your TSH level in the blood?

A TSH higher than normal may be a sign of the following diseases

  • Adrenal insufficiency
  • Secondary hyperthyroidism
  • Thyrotropinoma

What can I do to lower the TSH level in the blood?

TSH high values can be a consequence of an iodine deficiency. Iodine deficiency may be noted by an enlarged thyroid gland.

Some food such as cabbage or radishes should also be avoided.

It is probable that your doctor prescribe you a treatment with levothyroxine (a manufactured form of the thyroid hormone thyroxine T4). It may help you to reduce TSH levels.

Where can I find more information about TSH level in the blood?

You can visit our pages about:

Which values are considered a high TSH level in the blood?

The following values are considered to be above the normal range:

IMPORTANT: These levels are expressed in µUI/ml. They are an example of a healthy man of about 45 years old with no known disease and not taking any medication. The ranges can be different depending on the laboratory or on your personal circumstances.

TSH
Mild TSH increase
4.1 µUI/ml4.2 µUI/ml4.3 µUI/ml4.4 µUI/ml4.5 µUI/ml4.6 µUI/ml4.7 µUI/ml4.8 µUI/ml
4.9 µUI/ml5 µUI/ml5.1 µUI/ml5.2 µUI/ml5.3 µUI/ml5.4 µUI/ml5.5 µUI/ml5.6 µUI/ml
5.7 µUI/ml5.8 µUI/ml5.9 µUI/ml6 µUI/ml6.1 µUI/ml6.2 µUI/ml6.3 µUI/ml6.4 µUI/ml
6.5 µUI/ml6.6 µUI/ml6.7 µUI/ml6.8 µUI/ml6.9 µUI/ml7 µUI/ml7.1 µUI/ml7.2 µUI/ml
7.3 µUI/ml7.4 µUI/ml7.5 µUI/ml7.6 µUI/ml7.7 µUI/ml7.8 µUI/ml7.9 µUI/ml8 µUI/ml
8.1 µUI/ml8.2 µUI/ml8.3 µUI/ml8.4 µUI/ml8.5 µUI/ml8.6 µUI/ml8.7 µUI/ml8.8 µUI/ml
8.9 µUI/ml9 µUI/ml9.1 µUI/ml9.2 µUI/ml9.3 µUI/ml9.4 µUI/ml9.5 µUI/ml9.6 µUI/ml
9.7 µUI/ml9.8 µUI/ml9.9 µUI/ml10 µUI/ml    
Marked TSH increase
10.1 µUI/ml10.2 µUI/ml10.3 µUI/ml10.4 µUI/ml10.5 µUI/ml10.6 µUI/ml10.7 µUI/ml10.8 µUI/ml
10.9 µUI/ml11 µUI/ml11.1 µUI/ml11.2 µUI/ml11.3 µUI/ml11.4 µUI/ml11.5 µUI/ml11.6 µUI/ml
11.7 µUI/ml11.8 µUI/ml11.9 µUI/ml12 µUI/ml12.1 µUI/ml12.2 µUI/ml12.3 µUI/ml12.4 µUI/ml
12.5 µUI/ml12.6 µUI/ml12.7 µUI/ml12.8 µUI/ml12.9 µUI/ml13 µUI/ml13.1 µUI/ml13.2 µUI/ml
13.3 µUI/ml13.4 µUI/ml13.5 µUI/ml13.6 µUI/ml13.7 µUI/ml13.8 µUI/ml13.9 µUI/ml14 µUI/ml
14.1 µUI/ml14.2 µUI/ml14.3 µUI/ml14.4 µUI/ml14.5 µUI/ml14.6 µUI/ml14.7 µUI/ml14.8 µUI/ml
14.9 µUI/ml15 µUI/ml15.1 µUI/ml15.2 µUI/ml15.3 µUI/ml15.4 µUI/ml15.5 µUI/ml15.6 µUI/ml
15.7 µUI/ml15.8 µUI/ml15.9 µUI/ml16 µUI/ml16.1 µUI/ml16.2 µUI/ml16.3 µUI/ml16.4 µUI/ml
16.5 µUI/ml16.6 µUI/ml16.7 µUI/ml16.8 µUI/ml16.9 µUI/ml17 µUI/ml17.1 µUI/ml17.2 µUI/ml
17.3 µUI/ml17.4 µUI/ml17.5 µUI/ml17.6 µUI/ml17.7 µUI/ml17.8 µUI/ml17.9 µUI/ml18 µUI/ml
18.1 µUI/ml18.2 µUI/ml18.3 µUI/ml18.4 µUI/ml18.5 µUI/ml18.6 µUI/ml18.7 µUI/ml18.8 µUI/ml
18.9 µUI/ml19 µUI/ml19.1 µUI/ml19.2 µUI/ml19.3 µUI/ml19.4 µUI/ml19.5 µUI/ml19.6 µUI/ml
19.7 µUI/ml19.8 µUI/ml19.9 µUI/ml20 µUI/ml20.1 µUI/ml20.2 µUI/ml20.3 µUI/ml20.4 µUI/ml
20.5 µUI/ml20.6 µUI/ml20.7 µUI/ml20.8 µUI/ml20.9 µUI/ml21 µUI/ml21.1 µUI/ml21.2 µUI/ml
21.3 µUI/ml21.4 µUI/ml21.5 µUI/ml21.6 µUI/ml21.7 µUI/ml21.8 µUI/ml21.9 µUI/ml22 µUI/ml
22.1 µUI/ml22.2 µUI/ml22.3 µUI/ml22.4 µUI/ml22.5 µUI/ml22.6 µUI/ml22.7 µUI/ml22.8 µUI/ml
22.9 µUI/ml23 µUI/ml23.1 µUI/ml23.2 µUI/ml23.3 µUI/ml23.4 µUI/ml23.5 µUI/ml23.6 µUI/ml
23.7 µUI/ml23.8 µUI/ml23.9 µUI/ml24 µUI/ml24.1 µUI/ml24.2 µUI/ml24.3 µUI/ml24.4 µUI/ml
24.5 µUI/ml24.6 µUI/ml24.7 µUI/ml24.8 µUI/ml24.9 µUI/ml25 µUI/ml25.1 µUI/ml25.2 µUI/ml
25.3 µUI/ml25.4 µUI/ml25.5 µUI/ml25.6 µUI/ml25.7 µUI/ml25.8 µUI/ml25.9 µUI/ml26 µUI/ml
26.1 µUI/ml26.2 µUI/ml26.3 µUI/ml26.4 µUI/ml26.5 µUI/ml26.6 µUI/ml26.7 µUI/ml26.8 µUI/ml
26.9 µUI/ml27 µUI/ml27.1 µUI/ml27.2 µUI/ml27.3 µUI/ml27.4 µUI/ml27.5 µUI/ml27.6 µUI/ml
27.7 µUI/ml27.8 µUI/ml27.9 µUI/ml28 µUI/ml28.1 µUI/ml28.2 µUI/ml28.3 µUI/ml28.4 µUI/ml
28.5 µUI/ml28.6 µUI/ml28.7 µUI/ml28.8 µUI/ml28.9 µUI/ml29 µUI/ml29.1 µUI/ml29.2 µUI/ml
29.3 µUI/ml29.4 µUI/ml29.5 µUI/ml29.6 µUI/ml29.7 µUI/ml29.8 µUI/ml29.9 µUI/ml30 µUI/ml
30.1 µUI/ml30.2 µUI/ml30.3 µUI/ml30.4 µUI/ml30.5 µUI/ml30.6 µUI/ml30.7 µUI/ml30.8 µUI/ml
30.9 µUI/ml31 µUI/ml31.1 µUI/ml31.2 µUI/ml31.3 µUI/ml31.4 µUI/ml31.5 µUI/ml31.6 µUI/ml
31.7 µUI/ml31.8 µUI/ml31.9 µUI/ml32 µUI/ml32.1 µUI/ml32.2 µUI/ml32.3 µUI/ml32.4 µUI/ml
32.5 µUI/ml32.6 µUI/ml32.7 µUI/ml32.8 µUI/ml32.9 µUI/ml33 µUI/ml33.1 µUI/ml33.2 µUI/ml
33.3 µUI/ml33.4 µUI/ml33.5 µUI/ml33.6 µUI/ml33.7 µUI/ml33.8 µUI/ml33.9 µUI/ml34 µUI/ml
34.1 µUI/ml34.2 µUI/ml34.3 µUI/ml34.4 µUI/ml34.5 µUI/ml34.6 µUI/ml34.7 µUI/ml34.8 µUI/ml
34.9 µUI/ml35 µUI/ml35.1 µUI/ml35.2 µUI/ml35.3 µUI/ml35.4 µUI/ml35.5 µUI/ml35.6 µUI/ml
35.7 µUI/ml35.8 µUI/ml35.9 µUI/ml36 µUI/ml36.1 µUI/ml36.2 µUI/ml36.3 µUI/ml36.4 µUI/ml
36.5 µUI/ml36.6 µUI/ml36.7 µUI/ml36.8 µUI/ml36.9 µUI/ml37 µUI/ml37.1 µUI/ml37.2 µUI/ml
37.3 µUI/ml37.4 µUI/ml37.5 µUI/ml37.6 µUI/ml37.7 µUI/ml37.8 µUI/ml37.9 µUI/ml38 µUI/ml
38.1 µUI/ml38.2 µUI/ml38.3 µUI/ml38.4 µUI/ml38.5 µUI/ml38.6 µUI/ml38.7 µUI/ml38.8 µUI/ml
38.9 µUI/ml39 µUI/ml39.1 µUI/ml39.2 µUI/ml39.3 µUI/ml39.4 µUI/ml39.5 µUI/ml39.6 µUI/ml
39.7 µUI/ml39.8 µUI/ml39.9 µUI/ml40 µUI/ml40.1 µUI/ml40.2 µUI/ml40.3 µUI/ml40.4 µUI/ml
40.5 µUI/ml40.6 µUI/ml40.7 µUI/ml40.8 µUI/ml40.9 µUI/ml41 µUI/ml41.1 µUI/ml41.2 µUI/ml
41.3 µUI/ml41.4 µUI/ml41.5 µUI/ml41.6 µUI/ml41.7 µUI/ml41.8 µUI/ml41.9 µUI/ml42 µUI/ml
42.1 µUI/ml42.2 µUI/ml42.3 µUI/ml42.4 µUI/ml42.5 µUI/ml42.6 µUI/ml42.7 µUI/ml42.8 µUI/ml
42.9 µUI/ml43 µUI/ml43.1 µUI/ml43.2 µUI/ml43.3 µUI/ml43.4 µUI/ml43.5 µUI/ml43.6 µUI/ml
43.7 µUI/ml43.8 µUI/ml43.9 µUI/ml44 µUI/ml44.1 µUI/ml44.2 µUI/ml44.3 µUI/ml44.4 µUI/ml
44.5 µUI/ml44.6 µUI/ml44.7 µUI/ml44.8 µUI/ml44.9 µUI/ml45 µUI/ml45.1 µUI/ml45.2 µUI/ml
45.3 µUI/ml45.4 µUI/ml45.5 µUI/ml45.6 µUI/ml45.7 µUI/ml45.8 µUI/ml45.9 µUI/ml46 µUI/ml
46.1 µUI/ml46.2 µUI/ml46.3 µUI/ml46.4 µUI/ml46.5 µUI/ml46.6 µUI/ml46.7 µUI/ml46.8 µUI/ml
46.9 µUI/ml47 µUI/ml47.1 µUI/ml47.2 µUI/ml47.3 µUI/ml47.4 µUI/ml47.5 µUI/ml47.6 µUI/ml
47.7 µUI/ml47.8 µUI/ml47.9 µUI/ml48 µUI/ml48.1 µUI/ml48.2 µUI/ml48.3 µUI/ml48.4 µUI/ml
48.5 µUI/ml48.6 µUI/ml48.7 µUI/ml48.8 µUI/ml48.9 µUI/ml49 µUI/ml49.1 µUI/ml49.2 µUI/ml
49.3 µUI/ml49.4 µUI/ml49.5 µUI/ml49.6 µUI/ml49.7 µUI/ml49.8 µUI/ml49.9 µUI/ml50 µUI/ml
50.1 µUI/ml50.2 µUI/ml50.3 µUI/ml50.4 µUI/ml50.5 µUI/ml50.6 µUI/ml50.7 µUI/ml50.8 µUI/ml
50.9 µUI/ml51 µUI/ml51.1 µUI/ml51.2 µUI/ml51.3 µUI/ml51.4 µUI/ml51.5 µUI/ml51.6 µUI/ml
51.7 µUI/ml51.8 µUI/ml51.9 µUI/ml52 µUI/ml52.1 µUI/ml52.2 µUI/ml52.3 µUI/ml52.4 µUI/ml
52.5 µUI/ml52.6 µUI/ml52.7 µUI/ml52.8 µUI/ml52.9 µUI/ml53 µUI/ml53.1 µUI/ml53.2 µUI/ml
53.3 µUI/ml53.4 µUI/ml53.5 µUI/ml53.6 µUI/ml53.7 µUI/ml53.8 µUI/ml53.9 µUI/ml54 µUI/ml
54.1 µUI/ml54.2 µUI/ml54.3 µUI/ml54.4 µUI/ml54.5 µUI/ml54.6 µUI/ml54.7 µUI/ml54.8 µUI/ml
54.9 µUI/ml55 µUI/ml55.1 µUI/ml55.2 µUI/ml55.3 µUI/ml55.4 µUI/ml55.5 µUI/ml55.6 µUI/ml
55.7 µUI/ml55.8 µUI/ml55.9 µUI/ml56 µUI/ml56.1 µUI/ml56.2 µUI/ml56.3 µUI/ml56.4 µUI/ml
56.5 µUI/ml56.6 µUI/ml56.7 µUI/ml56.8 µUI/ml56.9 µUI/ml57 µUI/ml57.1 µUI/ml57.2 µUI/ml
57.3 µUI/ml57.4 µUI/ml57.5 µUI/ml57.6 µUI/ml57.7 µUI/ml57.8 µUI/ml57.9 µUI/ml58 µUI/ml
Medically reviewed by our Medical staff on 22/10/2020

Bibliography

  • Approved Guideline – Procedures for the Handling and Processing of Blood Specimens, H18-A3. 2004. Clinical and Laboratory Standards Institute.
  • HHS Publication, 6th ed., June 2020. Biosafety in Microbiological and Biomedical Laboratories. Available on: https://www.cdc.gov
  • Concise Book of Medical Laboratory Technology: Methods and Interpretations. 2nd Edition. 2015. Ramnik Sood. ISBN: 978-93-5152-333-8. Pag. 783.
  • Tietz. Fundamentals of Clinical Chemistry. Carl A. Burtis, Edward R. Ashwood, David E. Bruns, Barbara G. Sawyer. WB Saunders Company, 2008. Pag 766. ISBN: 978-0-7216-3865-2.
  • Laboratory tests and diagnostic procedures with nursing diagnoses (8th ed), Jane Vincent Corbett, Angela Denise Banks, ISBN: 978-0-13-237332-6, Pag. 400.

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